Insulin Treatment in Hospitalized Patients

Insulin Therapy in Hospitalized Patients

Hyperglycemia occurs frequently in hospitalized patients and many studies have shown that hyperglycemia is associated with poor outcomes. Until recently was considered that hyperglycemia does not significantly influence the patients outcome. This changed with the publication of Van den Berghe study, which demonstrated significant reduction in mortality with intensive glycemic management. Recent...

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چکیده ندارد.

Intensive insulin therapy in hospitalized patients: a systematic review.

BACKGROUND The benefits and harms of intensive insulin therapy (IIT) titrated to strict glycemic targets in hospitalized patients remain uncertain. PURPOSE To evaluate the benefits and harms of IIT in hospitalized patients. DATA SOURCES MEDLINE and Cochrane Database of Systematic Reviews from 1950 to January 2010, reference lists, experts, and unpublished sources. STUDY SELECTION English-...

Insulin Use in Hospitalized Patients With Diabetes: Navigate With Care

Insulin therapy for the management of hyperglycemia in hospitalized patients.

It has long been established that hyperglycemia with or without a prior diagnosis of diabetes increases both mortality and disease-specific morbidity in hospitalized patients and that goal-directed insulin therapy can improve outcomes. This article reviews the pathophysiology of hyperglycemia during illness, the mechanisms for increased complications and mortality due to hyperglycemia and hypog...